The iconic sci-fi series has already seen 12 actors take on the main role, the first being William Hartnell who originated the part on the BBC in 1963.
There are decades of history behind Doctor Who, and no doubt fans are champing at the bit to see how Jodie does in her new role.
But also joining her along the way are the Doctor’s new companions, Graham O’Brien (played by Bradley Walsh), Yasmin Khan (Mandip Gill) and Ryan Sinclair (Tosin Cole).
In an appearance on Sunday Brunch this morning, Yasmin star Mandip spoke out about her co-star Jodie.
In the interview with hosts Simon Rimmer and Tim Lovejoy, Mandip divulged that the pressure of the iconic role didn’t seem to faze Jodie.
She said: ”I’m not quite sure she understands the gravitas of it because she just takes it in her stride and is really cool about it.
“It’s a massive responsibility.
“I genuinely don’t think I would be able to do what she does – the amount of lines she learns on a daily basis!”
Mandip also went on to discuss how Jodie, 36, performed in the role where she praised the actress.
“She’s absolutely great, and I’m not just saying this because she’s a friend,” the 30-year-old shared.
“She just genuinely has nailed it. She’s the Doctor – she literally is the Doctor.
“There were no, ‘Maybe she’ll become the Doctor in a few episodes’. She completely is.”
Although the show is yet to air, Mandip and her co-stars have already hit some fans conventions.
But Sandip revealed that on a visit to San Diego Comic Con, she was able to walk around unrecognised.
However, the same couldn’t be said for Jodie as Madip spilled: “They [fans] definitely know who Jodie is.
“I can just speak for myself, I could just walk around freely.”
On what will happen after the episode airs tonight, Mandip said she would be willing to “embrace” any changes that come.
“I don’t know what to expect. I will embrace it if there is change.
“But I’d like to be able to go into town with no make-up on!”
Doctor Who returns tonight at 6.45pm on BBC One.